TMEM60 and CNR2

Data Source:
BioGRID (two hybrid)

		TMEM60	CNR2
Description		transmembrane protein 60	cannabinoid receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perikaryon
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Cannabinoid Receptor Activity Protein Binding
	Biological Process		Response To Amphetamine Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Metabolic Process Sensory Perception Of Pain Leukocyte Chemotaxis Negative Regulation Of Synaptic Transmission, GABAergic Response To Lipopolysaccharide Negative Regulation Of Mast Cell Activation Cannabinoid Signaling Pathway Negative Regulation Of Action Potential Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Activity
Pathways			Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events
Drugs			Dronabinol Nabilone Ricinoleic Acid Lasofoxifene Cannabidiol Tetrahydrocannabivarin Medical Cannabis Nabiximols
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31152163 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199)	Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494) Monocyte count ( 32888494) Multiple sclerosis ( 31604244) Psychotic experience (distressing) ( 31553412)
Interacting Genes		89 interacting genes: AMIGO1 ANKS6 APOL2 AQP2 AQP6 ASGR2 BEST2 BIK BSND CD300A CD53 CD74 CLDN7 CNR2 CPLX4 CYB5R3 EBP EDA ERGIC3 EVI2B FAM209A FFAR2 FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPR42 GPX8 HERPUD2 HIBADH HSD17B13 IFNGR2 KCNK5 KIAA2013 LEUTX LHFPL5 LMNA LRRC3B LRRC59 MFF MGST3 MMD MMGT1 PAGE1 PGRMC2 PI16 REEP2 REEP4 RETREG3 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC13A4 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC30A4 SLC35E3 SLC38A1 SLC39A2 SLC4A1 SLC7A8 SPAG4 SPNS3 SSMEM1 STOM STX1A SYT1 THAP4 TLCD4 TMCO5A TMED9 TMEM139 TMEM14B TMEM203 TMEM237 TMEM45B TMEM52B TMEM86B TMEM9 TMPPE TMPRSS2 TTYH1 VMA21	24 interacting genes: ADAM21 ADIPOQ AGPAT4 CCL4 COMT FXYD3 GNA15 MUC15 NRM PEDS1-UBE2V1 RFT1 SELENOK SLC35E4 SLC39A2 TMEM19 TMEM203 TMEM242 TMEM60 TMEM86A TMPPE TSPO2 YIPF1 YIPF4 YIPF6
Entrez ID		85025	1269
HPRD ID		12923	05444
Ensembl ID		ENSG00000135211	ENSG00000188822
Uniprot IDs		Q9H2L4	A0A024RAH7 P34972
PDB IDs			2KI9 5ZTY 6KPC 6KPF 6PT0
Enriched GO Terms of Interacting Partners?
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