PHYKPL and USO1

Data Source:
BioGRID (two hybrid)

		PHYKPL	USO1
Description		5-phosphohydroxy-L-lysine phospho-lyase	USO1 vesicle transport factor
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix	Golgi Membrane Fibrillar Center Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Transaminase Activity Lyase Activity Pyridoxal Phosphate Binding Identical Protein Binding	RNA Binding Protein Binding Cadherin Binding
	Biological Process	Lysine Catabolic Process Collagen Catabolic Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Small GTPase Mediated Signal Transduction Secretory Granule Localization Transcytosis COPII Vesicle Coating Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Cellular Response To Insulin Stimulus
Pathways		Collagen degradation Lysine catabolism	Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs		Pyridoxal phosphate Alanine
Diseases
GWAS			Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763)
Interacting Genes		4 interacting genes: LNX2 POT1 USO1 VAC14	25 interacting genes: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A RPL9 SCFD1 STX5 STXBP1 XPO7 YKT6
Entrez ID		85007	8615
HPRD ID		18482	09135
Ensembl ID		ENSG00000175309	ENSG00000138768
Uniprot IDs		Q8IUZ5	O60763
PDB IDs			2W3C
Enriched GO Terms of Interacting Partners?
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