MASTL and GPR158

Data Source:
BioGRID (two hybrid)

		MASTL	GPR158
Description		microtubule associated serine/threonine kinase like	G protein-coupled receptor 158
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cleavage Furrow	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Protein Phosphatase 2A Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	G Protein-coupled Receptor Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Peptidyl-serine Phosphorylation Negative Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Cell Division Regulation Of Cell Cycle	G Protein-coupled Receptor Signaling Pathway Protein Localization To Plasma Membrane
Pathways		MASTL Facilitates Mitotic Progression MASTL Facilitates Mitotic Progression
Drugs
Diseases		Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
GWAS		Plateletcrit ( 32888494 27863252) Squamous cell lung carcinoma ( 28604730)	Carboplatin disposition in epthelial ovarian cancer ( 29367611) Central corneal thickness ( 32528159) Cerebellum white matter volume ( 31530798) Diverticular disease ( 30177863 30661054) Energy expenditure (24h) ( 28476931) Hepatitis C (spontaneous viral clearance) ( 30593799) Immune response to smallpox vaccine (IL-6) ( 22542470) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998 29235454) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		1 interacting genes: CDC42
Entrez ID		84930	57512
HPRD ID		10499	13601
Ensembl ID		ENSG00000120539	ENSG00000151025
Uniprot IDs		Q96GX5	Q5T848
PDB IDs		5LOH
Enriched GO Terms of Interacting Partners?
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