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MASTL

Description microtubule associated serine/threonine kinase like
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Centrosome
  • Cleavage Furrow
Molecular Function
  • Protein Serine/threonine Kinase Activity
  • ATP Binding
  • Kinase Activity
  • Protein Phosphatase 2A Binding
  • Protein Serine Kinase Activity
  • Protein Threonine Kinase Activity
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Mitotic Cell Cycle
  • Cellular Response To DNA Damage Stimulus
  • Peptidyl-serine Phosphorylation
  • Negative Regulation Of Phosphoprotein Phosphatase Activity
  • Intracellular Signal Transduction
  • Cell Division
  • Regulation Of Cell Cycle
Pathways
  • MASTL Facilitates Mitotic Progression
  • MASTL Facilitates Mitotic Progression
Drugs
Diseases
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
GWAS
  • Plateletcrit ( 32888494 27863252)
  • Squamous cell lung carcinoma ( 28604730)
Novel Interacting Genes 1 novel interacting genes: GPR158
Interacting Genes 1 interacting genes: CDC42
Entrez ID 84930
HPRD ID 10499
Ensembl ID ENSG00000120539
Uniprot IDs Q96GX5
PDB IDs 5LOH
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025