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AOPEP and BMPR1A
Data Source:
BioGRID
(two hybrid)
AOPEP
BMPR1A
Description
aminopeptidase O (putative)
bone morphogenetic protein receptor type 1A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Cytosol
Plasma Membrane
Caveola
External Side Of Plasma Membrane
Integral Component Of Membrane
Dendrite
Neuronal Cell Body
Receptor Complex
HFE-transferrin Receptor Complex
Molecular Function
Zinc Ion Binding
Metalloaminopeptidase Activity
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta Receptor Activity, Type I
Protein Binding
ATP Binding
Protein Homodimerization Activity
SMAD Binding
Metal Ion Binding
BMP Receptor Activity
Biological Process
Angiotensin Maturation
In Utero Embryonic Development
Mesoderm Formation
Somitogenesis
Mullerian Duct Regression
Positive Regulation Of Mesenchymal Cell Proliferation
Chondrocyte Differentiation
Outflow Tract Septum Morphogenesis
Outflow Tract Morphogenesis
Cardiac Conduction System Development
Mitral Valve Morphogenesis
Tricuspid Valve Morphogenesis
Endocardial Cushion Morphogenesis
Cardiac Right Ventricle Morphogenesis
Ventricular Trabecula Myocardium Morphogenesis
Ventricular Compact Myocardium Morphogenesis
Endocardial Cushion Formation
Protein Phosphorylation
Immune Response
Transforming Growth Factor Beta Receptor Signaling Pathway
Ectoderm Development
Dorsal/ventral Axis Specification
Dorsal/ventral Pattern Formation
Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Neural Crest Cell Development
Negative Regulation Of Smooth Muscle Cell Migration
Stem Cell Population Maintenance
Pituitary Gland Development
Neural Plate Mediolateral Regionalization
Lung Development
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Hindlimb Morphogenesis
Dorsal Aorta Morphogenesis
Odontogenesis Of Dentin-containing Tooth
Embryonic Digit Morphogenesis
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Paraxial Mesoderm Structural Organization
Lateral Mesoderm Development
Regulation Of Lateral Mesodermal Cell Fate Specification
Mesendoderm Development
Embryonic Organ Development
Developmental Growth
Positive Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Neurogenesis
Roof Of Mouth Development
Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Positive Regulation Of SMAD Protein Signal Transduction
Heart Formation
BMP Signaling Pathway Involved In Heart Development
Pharyngeal Arch Artery Morphogenesis
Cellular Response To Growth Factor Stimulus
Cellular Response To BMP Stimulus
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Cardiac Ventricle Development
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Fibrous Ring Of Heart Morphogenesis
Regulation Of Neural Crest Cell Differentiation
Regulation Of Cellular Senescence
Pathways
Metabolism of Angiotensinogen to Angiotensins
Signaling by BMP
Drugs
Dibotermin alfa
Diseases
Hereditary mixed polyposis syndrome
Juvenile polyposis syndrome
GWAS
Apolipoprotein A1 levels (
32203549
)
HDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
White blood cell count (
32888494
)
Interacting Genes
9 interacting genes:
BMPR1A
BUB1
CDH1
CDKN2A
DLC1
EGFR
MLH3
NRAS
SMAD4
45 interacting genes:
ACVR1
ALDOB
AOPEP
BAMBI
BMP2
BMP4
BMP5
BMP6
BMP7
BMPR1B
BMPR2
CDK8
CTSV
FANCC
FBP1
FBP2
FKBP1A
FKBP1B
GALNT12
GDF5
GDF6
GDF9
HOXC8
HRAS
IGFBP3
MAP2K1
MSANTD3
NEDD4
NEDD4L
OTUB1
RASA1
SEC61B
SF3B4
SFRP2
SFRP4
SMAD1
TAB1
TDGF1
TGFB1
TGFBRAP1
TRMO
USP15
XPA
ZMYND11
ZNF189
Entrez ID
84909
657
HPRD ID
07476
03192
Ensembl ID
ENSG00000148120
ENSG00000107779
Uniprot IDs
Q8N6M6
P36894
PDB IDs
1ES7
1REW
2GOO
2H62
2H64
2K3G
2QJ9
2QJA
2QJB
3NH7
3QB4
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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