FBH1 and RPL13A

Data Source:
HPRD (two hybrid)

		FBH1	RPL13A
Description		F-box DNA helicase 1	ribosomal protein L13a
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus SCF Ubiquitin Ligase Complex	Nucleus Nucleolus Cytoplasm Cytosol Ribosome Focal Adhesion Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit GAIT Complex Ribonucleoprotein Complex
	Molecular Function	DNA Helicase Activity Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA Translocase Activity 3'-5' DNA Helicase Activity	RNA Binding MRNA Binding Structural Constituent Of Ribosome
	Biological Process	Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Catabolic Process, Endonucleolytic Positive Regulation Of Protein Phosphorylation Cellular Response To DNA Damage Stimulus Cell Death Protein Ubiquitination Replication Fork Processing DNA Duplex Unwinding Negative Regulation Of Chromatin Binding Replication Fork Protection Response To Intra-S DNA Damage Checkpoint Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Double-strand Break Repair Via Homologous Recombination	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Negative Regulation Of Translation Viral Transcription Cellular Response To Interferon-gamma Negative Regulation Of Formation Of Translation Preinitiation Complex
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			(S)-3-phenyllactic acid Anisomycin Puromycin
Diseases
GWAS			Hematological and biochemical traits ( 20139978)
Interacting Genes		9 interacting genes: CUL1 ESR1 PIM2 RAD51 RBX1 RPL13A SKP1 UBC ZDHHC17	14 interacting genes: ALDH2 ALG12 CALM1 CRP CYP2E1 ETS1 FBH1 FNTA GOLM1 MT-ND1 NOD2 PTEN STOM VTN
Entrez ID		84893	23521
HPRD ID		06243	11775
Ensembl ID		ENSG00000134452	ENSG00000142541
Uniprot IDs		B3KV95 F6UZG9 Q2TAK1 Q8NFZ0	A0A384ME37 P40429 Q8J015
PDB IDs			4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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