OFD1 and EGFL6

Data Source:
BioGRID (affinity chromatography technology)

		OFD1	EGFL6
Description		OFD1 centriole and centriolar satellite protein	EGF like domain multiple 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body	Basement Membrane Extracellular Space Membrane
	Molecular Function	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding	Integrin Binding Calcium Ion Binding Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking	Cell Adhesion Multicellular Organism Development Positive Regulation Of Cell-substrate Adhesion Cell Differentiation Extracellular Matrix Organization
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Oral-facial-digital syndrome 1 Joubert syndrome
GWAS			Acute post-radiotherapy pain in breast cancer ( 31196165) Multiple sclerosis ( 23412934)
Interacting Genes		8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6	3 interacting genes: SH3GL2 SH3GL3 UBQLN2
Entrez ID		8481	25975
HPRD ID		02162	02212
Ensembl ID		ENSG00000046651	ENSG00000198759
Uniprot IDs		A6NF31 E9KL37 O75665	Q8IUX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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