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CBX2 and KRTAP2-4
Data Source:
BioGRID
(two hybrid)
CBX2
KRTAP2-4
Description
chromobox 2
keratin associated protein 2-4
Image
No pdb structure
GO Annotations
Cellular Component
Euchromatin
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Cytosol
Keratin Filament
Molecular Function
DNA Binding
Chromatin Binding
Protein Binding
Methylated Histone Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Cell Differentiation
Development Of Primary Sexual Characteristics
Keratinization
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Keratinization
Keratinization
Drugs
Diseases
46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Brain morphology (MOSTest) (
32665545
)
Interacting Genes
25 interacting genes:
BOLL
CYSRT1
DHX57
H3-4
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP12-2
KRTAP12-3
KRTAP2-4
KRTAP4-12
KRTAP4-4
MDFI
MEOX2
PCGF2
PHC2
RBMY1A1
RBMY1F
RBMY1J
RBPMS2
RNF2
RYBP
TRIM55
TRIM63
95 interacting genes:
ADAMTSL3
BAHD1
BCL6B
BEX2
C11orf87
CATSPER1
CBX2
CHIC2
CNNM3
CREB5
CTSZ
CXCL16
CYSRT1
DHX57
DMRT3
FAM161A
GEMIN4
GGN
HAPLN2
HHEX
HOXA1
HOXB9
IGSF8
ITGB4
JOSD1
KLHL38
KRTAP1-1
KRTAP10-1
KRTAP10-5
KRTAP12-4
KRTAP4-11
KRTAP4-12
KRTAP4-4
KRTAP5-11
KRTAP5-2
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1B
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LNX1
MCRS1
MOBP
NBPF19
NKD1
NOTCH2NLA
NPDC1
NUFIP2
OTX1
P2RY6
PHLDA1
PIGS
PRKAB2
PTPMT1
RHBDL1
RPS28
SDC3
SHFL
SPATA3
SPRED2
TFAP2D
TMEM190
TNP2
TRIM42
TTPA
VASN
VWC2
YY1
ZBTB24
ZDHHC1
ZIM2
ZNF165
ZNF264
ZNF440
ZNF491
ZNF524
ZNF564
ZNF575
ZNF578
ZNF581
ZNF587
ZNF672
ZNF764
ZNF786
ZNF792
Entrez ID
84733
85294
HPRD ID
14397
13936
Ensembl ID
ENSG00000173894
ENSG00000213417
Uniprot IDs
Q14781
P0C7H8
Q9BYR9
PDB IDs
2D9U
3H91
5EPK
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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