MCEE and PPP1R16B

Data Source:
BioGRID (biochemical)

		MCEE	PPP1R16B
Description		methylmalonyl-CoA epimerase	protein phosphatase 1 regulatory subunit 16B
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Matrix	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Methylmalonyl-CoA Epimerase Activity Protein Binding Metal Ion Binding	Protein Binding Protein Phosphatase 1 Binding Myosin Phosphatase Regulator Activity Protein Phosphatase Regulator Activity
	Biological Process	Short-chain Fatty Acid Catabolic Process L-methylmalonyl-CoA Metabolic Process	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Sprouting Angiogenesis
Pathways		Propionyl-CoA catabolism
Drugs
Diseases		Methylmalonic aciduria (MMA)
GWAS		Erythema nodosum in inflammatory bowel disease ( 24487271) Metabolite levels ( 23823483)	Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Mean corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		5 interacting genes: AGTRAP APP CD81 CMTM5 STX8	37 interacting genes: ATPAF2 CDCA7L CEP55 CEP70 CRX DVL2 DVL3 FAM83A FARS2 FLYWCH1 GATA1 GFAP GOLGA2 HAPLN2 IKZF3 KCTD9 MAGOH MISP NEFL PATZ1 PHC2 PLEKHN1 PPP1CA PPP1CB RBPMS RFC5 SCNM1 SF3B4 SHC3 TACO1 TADA2A TASOR2 TFIP11 TLE5 TXN2 ZNF410 ZNF564
Entrez ID		84693	26051
HPRD ID		12229	15168
Ensembl ID		ENSG00000124370	ENSG00000101445
Uniprot IDs		Q96PE7	Q96T49
PDB IDs		3RMU 6QH4
Enriched GO Terms of Interacting Partners?
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