ACCS and UQCRB

Data Source:
BioGRID (two hybrid)

		ACCS	UQCRB
Description		1-aminocyclopropane-1-carboxylate synthase homolog (inactive)	ubiquinol-cytochrome c reductase binding protein
Image		No pdb structure
GO Annotations	Cellular Component		Mitochondrial Inner Membrane Mitochondrial Respirasome Mitochondrial Respiratory Chain Complex III
	Molecular Function	Protein Binding 1-aminocyclopropane-1-carboxylate Synthase Activity Pyridoxal Phosphate Binding Identical Protein Binding	Protein Binding
	Biological Process	1-aminocyclopropane-1-carboxylate Biosynthetic Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration
Pathways			Respiratory electron transport
Drugs		Vinylglycine	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		IgA nephropathy ( 26028593)	Huntington's disease progression ( 28642124)
Interacting Genes		2 interacting genes: FBF1 UQCRB	9 interacting genes: ACAP1 ACCS HPCA HSPB1 LRRK2 MAGEA1 MAGEA4 MAGEB4 ZSWIM7
Entrez ID		84680	7381
HPRD ID		10524	11770
Ensembl ID		ENSG00000110455	ENSG00000156467
Uniprot IDs		A0A0S2Z622 Q96QU6	P14927
PDB IDs			5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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