HES7 and OSTF1

Data Source:
BioGRID (two hybrid)

		HES7	OSTF1
Description		hes family bHLH transcription factor 7	osteoclast stimulating factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Region Intracellular Anatomical Structure Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding SH3 Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal System Development Somitogenesis Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Mesoderm Development Anterior/posterior Pattern Specification Post-anal Tail Morphogenesis Rhythmic Process Regulation Of Neurogenesis	Ossification Signal Transduction Neutrophil Degranulation
Pathways			Neutrophil degranulation
Drugs
Diseases		Spondylocostal dysostosis (SCD)
GWAS		Height ( 25282103)	Allergic rhinitis ( 25085501) Glucose homeostasis traits ( 25524916) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Resting-state electroencephalogram vigilance ( 29703947) Systemic sclerosis ( 30247649) Urinary magnesium-to-creatinine ratio ( 29093028)
Interacting Genes		6 interacting genes: OSTF1 PIH1D2 PRPF31 QARS1 TCEA2 TCEANC	51 interacting genes: AGR2 APP BORCS6 CBL CBLB CCDC33 CRX CTDSP1 CUEDC1 DPPA4 DTX3 EFS ERRFI1 FASLG FBXO7 GAPDH GGN HES7 HTT KHDRBS1 KLHL42 LATS1 LMNA MAPK6 MED19 MEOX2 NFYC NUTM1 NUTM2F PBX4 PICK1 REL RP2 SDCBP SF1 SF3A2 SMN1 SNW1 SOCS7 SYNGAP1 TRIB3 TRIM54 VPS37B WASF1 WASHC1 WASL YPEL3 ZBTB42 ZBTB7B ZNF655 ZNF688
Entrez ID		84667	26578
HPRD ID		09729	17808
Ensembl ID		ENSG00000179111	ENSG00000134996
Uniprot IDs		Q9BYE0	Q92882
PDB IDs			1X2K 1ZLM 3EHQ 3EHR
Enriched GO Terms of Interacting Partners?
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