ZGPAT and CCDC57

Data Source:
BioGRID (two hybrid)

		ZGPAT	CCDC57
Description		zinc finger CCCH-type and G-patch domain containing	coiled-coil domain containing 57
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Plasma Membrane	Centrosome Centriole Spindle Microtubule Centriolar Satellite
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Transcription, DNA-templated	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) C-reactive protein levels ( 30388399) Crohn's disease ( 28067908) Diverticular disease ( 30177863) Estimated glomerular filtration rate ( 31152163 31015462) High density lipoprotein cholesterol levels ( 31928498) Inflammatory bowel disease ( 28067908 23128233) Lung function (FEV1) ( 28166213) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Prostate cancer ( 31562322 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908 21297633) Waist circumference ( 31928498)	Blood metabolite levels ( 24816252) Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		77 interacting genes: AIMP2 AMOTL2 BEND5 BLZF1 C1D CARD9 CAVIN4 CCDC13 CCDC196 CCDC33 CCDC57 CCHCR1 CCNDBP1 CDCA7L CDR2 CEP57L1 CEP70 CNKSR1 CTNNA1 DHX15 DVL2 DYDC1 EP400 FAM9B GATAD2B GOLGA2 GOLGA6L9 HOOK2 HSF2BP IHO1 IKZF3 KIAA1328 KIFC3 KRT15 KRT31 KRT40 LCA5L LDOC1 LNX1 LZTS1 LZTS2 MID2 MIPOL1 NEBL PHC2 PPP1R13B PRPF3 S100A10 SCNM1 SERTAD3 SNRPA1 SPAG5 SSX2IP STAC3 TADA2B TFIP11 THAP1 THAP6 TLE5 TP53BP2 TRIM14 TRIM27 TRIM54 UBXN11 UPF2 ZBTB8A ZC2HC1B ZNF177 ZNF24 ZNF329 ZNF426 ZNF559-ZNF177 ZNF587 ZNF688 ZNF71 ZSCAN22 ZXDB	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 C2CD6 C4orf45 C9orf24 CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PPP1R32 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		84619	284001
HPRD ID		15736	14150
Ensembl ID		ENSG00000197114	ENSG00000176155
Uniprot IDs		A0A0S2Z5X3 Q8N5A5	A0A590UJT6 Q2TAC2
PDB IDs		4II1
Enriched GO Terms of Interacting Partners?
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