KBTBD8 and NOLC1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		KBTBD8	NOLC1
Description		kelch repeat and BTB domain containing 8	nucleolar and coiled-body phosphoprotein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Spindle Cytosol Cul3-RING Ubiquitin Ligase Complex	Fibrillar Center Nucleoplasm Nucleolus Cytoplasm Cajal Body Box C/D RNP Complex Box H/ACA SnoRNP Complex
	Molecular Function	Protein Binding	DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding ATP Binding GTP Binding Transcription Factor Binding Nuclear Localization Sequence Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Box C/D RNA Binding Box H/ACA SnoRNA Binding Protein Heterodimerization Activity Box C/D SnoRNP Complex Binding Box H/ACA SnoRNP Complex Binding
	Biological Process	Regulation Of Translation Protein Monoubiquitination Neural Crest Formation Neural Crest Cell Development Post-translational Protein Modification	Mitotic Cell Cycle RRNA Processing Regulation Of Translation Response To Osmotic Stress Nucleolus Organization Positive Regulation Of Cell Population Proliferation Neural Crest Formation Neural Crest Cell Development Box H/ACA RNA Metabolic Process Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription, DNA-templated
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs			Doxorubicin
Diseases
GWAS		Alzheimer's disease ( 30636644) Blood urea nitrogen levels ( 29403010) Intraocular pressure ( 29617998 29785010 31959993) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Retinal detachment or retinal break ( 31816047) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Type 2 diabetes ( 25760438) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Triglyceride levels ( 32203549)
Interacting Genes		2 interacting genes: FBXL17 NOLC1	16 interacting genes: APP CEBPB COIL CSNK2A1 CSNK2B E2F4 ERG GTF2B KBTBD8 MDM2 POLR1A PRKACA SRPK2 USP4 YWHAG YWHAQ
Entrez ID		84541	9221
HPRD ID		18138	03864
Ensembl ID		ENSG00000163376	ENSG00000166197
Uniprot IDs		Q8NFY9	B2RAU8 Q14978 Q96J17
PDB IDs
Enriched GO Terms of Interacting Partners?
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