COA8 and TRMT61A

		COA8	TRMT61A
Description		cytochrome c oxidase assembly factor 8	tRNA methyltransferase 61A
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Matrix Side Of Mitochondrial Inner Membrane	Nucleus Nucleoplasm TRNA (m1A) Methyltransferase Complex
	Molecular Function		Protein Binding TRNA (adenine-N1-)-methyltransferase Activity MRNA (adenine-N1-)-methyltransferase Activity
	Biological Process	Response To Reactive Oxygen Species Mitochondrial Cytochrome C Oxidase Assembly Protein Stabilization Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Cytochrome-c Oxidase Activity	TRNA Modification TRNA Methylation MRNA Methylation
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Branched-chain amino acid levels (Isoleucine) ( 27898682) Extremely high intelligence ( 29520040) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494) Schizophrenia ( 25056061)
Interacting Genes			2 interacting genes: TCL1A TRMT6
Entrez ID		84334	115708
HPRD ID		12637	08810
Ensembl ID		ENSG00000256053	ENSG00000166166
Uniprot IDs		Q96IL0	A0A024R6Q2 Q96FX7
PDB IDs			5CCB 5CCX 5CD1
Enriched GO Terms of Interacting Partners?
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