MON1A and FYCO1

Data Source:
HPRD (in vivo)

		MON1A	FYCO1
Description		MON1 homolog A, secretory trafficking associated	FYVE and coiled-coil domain autophagy adaptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Mon1-Ccz1 Complex	Lysosome Late Endosome Autophagosome Golgi Apparatus Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Protein Targeting To Vacuole Protein Secretion Vesicle-mediated Transport Regulation Of Catalytic Activity	Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Autophagosome Maturation
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Body mass index ( 28892062 25673413 29273807) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Bone mineral content ( 31790847) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		6 interacting genes: GFI1B MAPK6 RABGEF1 RGS2 TAB1 VPS33A	4 interacting genes: APP KDM1A PRMT6 RAF1
Entrez ID		84315	79443
HPRD ID		17586	06215
Ensembl ID		ENSG00000164077	ENSG00000163820
Uniprot IDs		Q86VX9	Q9BQS8
PDB IDs			5CX3 5D94 7BQI
Enriched GO Terms of Interacting Partners?
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