MON1A and VPS33A

Data Source:
BioGRID (pull down)

		MON1A	VPS33A
Description		MON1 homolog A, secretory trafficking associated	VPS33A core subunit of CORVET and HOPS complexes
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Mon1-Ccz1 Complex	Lysosome Lysosomal Membrane Early Endosome Late Endosome Autophagosome AP-3 Adaptor Complex Clathrin-coated Vesicle HOPS Complex Late Endosome Membrane CORVET Complex Perinuclear Region Of Cytoplasm Clathrin Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding
	Biological Process	Protein Targeting To Vacuole Protein Secretion Vesicle-mediated Transport Regulation Of Catalytic Activity	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome To Lysosome Transport Vesicle-mediated Transport Platelet Formation Melanosome Localization Lysosome Localization Regulation Of Lysosomal Lumen PH Regulation Of Developmental Pigmentation Autophagosome Maturation
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Body mass index ( 28892062 25673413 29273807) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: GFI1B MAPK6 RABGEF1 RGS2 TAB1 VPS33A	7 interacting genes: MON1A MON1B ROPN1 TNKS VPS11 VPS16 VPS18
Entrez ID		84315	65082
HPRD ID		17586	15651
Ensembl ID		ENSG00000164077	ENSG00000139719
Uniprot IDs		Q86VX9	Q96AX1
PDB IDs			4BX8 4BX9
Enriched GO Terms of Interacting Partners?
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