CAPNS2 and RIN1

Data Source:
BioGRID (two hybrid)

		CAPNS2	RIN1
Description		calpain small subunit 2	Ras and Rab interactor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Cytoplasm Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Proteolysis Extracellular Matrix Disassembly	Endocytosis Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Degradation of the extracellular matrix Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Thyroid hormone levels ( 23408906)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		9 interacting genes: APP ARMC10 CAPN2 CMTM5 OXNAD1 PHACTR3 PPIC PRPF31 RIN1	50 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CCM2 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH NRAS PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1
Entrez ID		84290	9610
HPRD ID		16682	05813
Ensembl ID		ENSG00000256812	ENSG00000174791
Uniprot IDs		Q96L46	A0A0S2Z4U0 Q13671
PDB IDs
Enriched GO Terms of Interacting Partners?
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