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POLDIP3 and POLD2
Data Source:
HPRD
(two hybrid)
POLDIP3
POLD2
Description
DNA polymerase delta interacting protein 3
DNA polymerase delta 2, accessory subunit
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Speck
Cytoplasmic Ribonucleoprotein Granule
Nucleus
Nucleoplasm
Zeta DNA Polymerase Complex
DNA Polymerase Complex
Delta DNA Polymerase Complex
Molecular Function
RNA Binding
Protein Binding
Protein-containing Complex Binding
DNA Binding
Protein Binding
Biological Process
RNA Export From Nucleus
MRNA Export From Nucleus
Poly(A)+ MRNA Export From Nucleus
MRNA 3'-end Processing
Positive Regulation Of Translation
Telomere Maintenance
DNA Replication
DNA Strand Elongation Involved In DNA Replication
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Translesion Synthesis
Telomere Maintenance Via Semi-conservative Replication
Nucleotide-excision Repair, DNA Incision
DNA Damage Response, Detection Of DNA Damage
DNA Biosynthetic Process
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Recognition of DNA damage by PCNA-containing replication complex
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Removal of the Flap Intermediate from the C-strand
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand
Drugs
Diseases
GWAS
Interacting Genes
28 interacting genes:
BANP
BICD2
CCNDBP1
ERH
EXOSC8
GOLGA2
GTPBP3
HMBOX1
HOMEZ
HSF2BP
KRT31
KRT40
LZTS2
MID2
MTUS2
OSGIN1
OTX2
PIBF1
PNMA1
POLD2
POLR1C
RAD51D
RPS6KA1
RPS6KB1
SBK3
SRPK2
TEKT4
ZRANB1
18 interacting genes:
CCHCR1
CDK2
CDKN1A
EP300
ERBB2
KCTD13
LSM6
PCNA
POLD1
POLD3
POLD4
POLDIP2
POLDIP3
POLH
SOX12
WRN
WRNIP1
XRN1
Entrez ID
84271
5425
HPRD ID
17875
15982
Ensembl ID
ENSG00000100227
ENSG00000106628
Uniprot IDs
B4E0L0
F6VRR5
Q659C6
Q9BY77
A0A087WWF6
P49005
PDB IDs
3E0J
6S1M
6S1N
6S1O
6TNY
6TNZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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