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BFSP2 and ECSIT
Data Source:
BioGRID
(two hybrid)
BFSP2
ECSIT
Description
beaded filament structural protein 2
ECSIT signaling integrator
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Intermediate Filament
Plasma Membrane
Cell Cortex
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Cytosol
Molecular Function
Structural Constituent Of Cytoskeleton
Structural Constituent Of Eye Lens
Protein Binding
Protein Binding
Biological Process
Visual Perception
Intermediate Filament Organization
Cell Maturation
Response To Stimulus
Lens Fiber Cell Development
Mitochondrial Respiratory Chain Complex I Assembly
Innate Immune Response
Regulation Of Oxidoreductase Activity
Regulation Of Protein Complex Stability
Pathways
MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Complex I biogenesis
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
MyD88 cascade initiated on plasma membrane
Drugs
Diseases
GWAS
Presence of antiphospholipid antibodies (
27098658
)
Interacting Genes
56 interacting genes:
ABI3
AMOTL2
ANKRD33
ATF4
BEX3
BEX5
BFSP1
BICRAL
BLOC1S2
C3orf62
CAGE1
CALCOCO1
CCDC153
CCDC183
CDCA4
CDR2L
CEP44
CEP63
COPS6
CT55
DISC1
DMAP1
ECSIT
HAUS1
HGS
KRT14
KRT24
KRT27
KRT31
KRT37
MAGEA6
MBIP
MCCD1
MYOG
OIP5
PBX2
PBX4
POU6F2
PPP1R13B
PSMC5
RINT1
RNASE10
SAPCD2
SCOC
SERTAD3
SNAPC5
SNAPIN
SUFU
SYCE1
SYCE1L
TRIB3
USHBP1
USP54
WASHC3
ZNF343
ZNF620
52 interacting genes:
A2M
AP1M2
APOE
APP
BFSP2
BLMH
C1orf109
CDC37
CEP55
CTNNA3
CYP2C18
CYP2C8
CYP2C9
DNAJB1
DTX2
ELAVL3
EXOC6
EXOSC1
FARSA
FBXL12
FBXW4
GCDH
GEM
IFIT3
IFIT5
IMMT
LONP1
LOXL4
MAGEB2
MAST1
MKRN3
NFKB1
NXF1
PAXIP1
PI4K2A
PRDX2
PSEN1
RAB3A
RAD23A
RELA
RHEB
RNF32
SETDB1
SMAD1
SMAD4
SMURF1
STAMBPL1
STRN4
TARS3
TRAF6
TRIM59
TSSK3
Entrez ID
8419
51295
HPRD ID
04444
12225
Ensembl ID
ENSG00000170819
ENSG00000130159
Uniprot IDs
Q13515
Q9BQ95
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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