FAM161A and CTNNA3

Data Source:
BioGRID (two hybrid)

		FAM161A	CTNNA3
Description		FAM161 centrosomal protein A	catenin alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Astral Microtubule Photoreceptor Inner Segment Centrosome Spindle Microtubule Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Mitotic Spindle Mitotic Spindle Pole	Cytosol Cytoskeleton Adherens Junction Fascia Adherens Lamellipodium
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding	Protein Binding Beta-catenin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Visual Perception Cilium Organization Response To Stimulus Cilium Assembly Positive Regulation Of Protein Acetylation	Actin Filament Organization Cell Migration Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Epithelial Cell-cell Adhesion Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Atrial fibrillation ( 29892015) Erectile dysfunction ( 30583798) Systemic lupus erythematosus ( 28714469)	Adventurousness ( 30643258) Adverse response to drug ( 30420678) Asthma (toluene diisocyanate-induced) ( 19187332) Bronchopulmonary dysplasia ( 23897914) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dental caries ( 23064961) Diffusing capacity of carbon monoxide ( 30694715) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Essential tremor ( 27797806) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Lung function (FVC) ( 24023788) Metabolite levels ( 23823483) Metabolite levels (Pyroglutamine) ( 23934736) Mitochondrial DNA copy number ( 30704525) Nickel levels ( 26025379) Nicotine dependence ( 17158188) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Optic disc area ( 28073927) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878) Schizophrenia (cytomegalovirus infection interaction) ( 23358160) Subcutaneous adipose tissue ( 29178545) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 27841878)
Interacting Genes		139 interacting genes: AQP1 AXIN2 BACH2 BEGAIN BEND3 BEND5 BHLHB9 BICD2 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CBY2 CCDC102B CCDC125 CCDC13 CCDC136 CCDC185 CCDC33 CCDC57 CCDC88B CCNC CCNDBP1 CDR2 CDR2L CEP44 CEP57L1 CEP63 CEP70 CEP72 CTNNA3 DHX32 DOCK8 DVL2 EHMT2 EVI5 FAM9B FSD2 FXR1 GAS8 GOLGA2 GOLGA6L9 GPBP1 GRIPAP1 HEXIM2 HMBOX1 HOOK1 HOOK2 IKZF1 INO80E JRK KANK2 KASH5 KAT5 KDM1A KIAA0753 KIAA1328 KIFC3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP5-7 KRTAP5-9 LDOC1 LMNA LURAP1L LZTS1 LZTS2 MAGEA11 MCC MCM6 MDFI MID2 MIPOL1 MKRN1 MTUS2 NECAB2 NINL NUTM1 OSBPL3 PDE4DIP PHC2 PIBF1 PICK1 PLEKHG4 PNMA1 PNMA2 POC5 PPFIA1 PPM1F PPP2R3C PRKAR1B QARS1 RINT1 ROPN1 RUBCN RUNDC3A SCNM1 SMARCD1 SOGA1 SSX2IP STX11 SYCE1 TAX1BP1 TBC1D1 TFIP11 TMCC2 TNIP1 TNIP3 TRAF1 TRAF2 TRIB3 TRIM15 TRIM27 TRIM37 TRIM41 TRIM54 TRIM69 TSGA10 TXLNB VIM VPS52 ZBTB1 ZBTB14 ZBTB43 ZBTB8A ZIM2 ZNF24 ZNF250 ZNF276 ZNF426 ZNF526 ZNF792 ZRANB1 ZSCAN12	68 interacting genes: AKAP9 ATP23 BLOC1S2 BLZF1 C17orf50 CCDC183 CCDC33 CDSN CENPS-CORT CKMT1A CKMT1B CMC2 COG4 CRX CTNNB1 DISC1 ECSIT EID2B EPS8 FAM110A FAM161A FAM161B FAM9A FBXO28 FERD3L GINS3 GNB1 HDX HOMEZ JUP KATNAL1 LASP1 MARCHF7 MBD3L1 MSRA MYOG NAB2 NDUFB7 OIP5 ORC2 PAX6 PLAGL2 PNMA1 PNMA5 POU6F2 PPARA PRR5 REL RIPPLY1 RPS6KA5 SERTAD2 SPATS1 STMN2 TASOR2 TLX3 TNNI1 TNNI2 TRIM54 TXNRD3 USHBP1 VIP ZG16 ZNF19 ZNF426 ZNF474 ZNF552 ZNF620 ZNF662
Entrez ID		84140	29119
HPRD ID		18996	09639
Ensembl ID		ENSG00000170264	ENSG00000183230
Uniprot IDs		Q3B820	A8K141 Q8WW10 Q9UI47
PDB IDs
Enriched GO Terms of Interacting Partners?
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