DTNBP1 and DEK

Data Source:
BioGRID (pull down, pull down, proximity labelling technology)

		DTNBP1	DEK
Description		dystrobrevin binding protein 1	DEK proto-oncogene
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Postsynaptic Density Microtubule Cytoskeleton Sarcoplasm Axon Growth Cone Midbody Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Axon Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	Protein Binding	DNA Binding RNA Binding Protein Binding Histone Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Negative Regulation Of Protein Kinase Activity Blood Coagulation Anterograde Axonal Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Negative Regulation Of Protein Binding Melanosome Organization Regulation Of JUN Kinase Activity Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Dendrite Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Exocytosis	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Signal Transduction Viral Genome Replication Positive Regulation Of Gene Expression, Epigenetic Regulation Of Double-strand Break Repair
Pathways		Golgi Associated Vesicle Biogenesis	B-WICH complex positively regulates rRNA expression Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Corneal astigmatism ( 30306274) Multiple myeloma ( 27363682) Squamous cell carcinoma ( 31174203)	Atrial fibrillation ( 30061737) Metabolite levels ( 23823483) PR interval ( 32439900)
Interacting Genes		50 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S5 BLOC1S6 BRF1 CCDC146 CCDC153 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 KRT75 MACF1 NBEA NDN NECAB2 NUF2 OIP5 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM9 VRK2 WASHC3 ZNF490	14 interacting genes: AP2A1 CDC42 CREBBP CSNK2A1 EP300 GPATCH11 H3-4 HLA-A KAT2B SRRM1 TFAP2A TRIM55 TRIM63 ZIK1
Entrez ID		84062	7913
HPRD ID		06190	00503
Ensembl ID		ENSG00000047579	ENSG00000124795
Uniprot IDs		A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8	H0Y993 P35659
PDB IDs			1Q1V 2JX3
Enriched GO Terms of Interacting Partners?
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