DTNBP1 and ZNF490

Data Source:
BioGRID (two hybrid)

		DTNBP1	ZNF490
Description		dystrobrevin binding protein 1	zinc finger protein 490
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Postsynaptic Density Microtubule Cytoskeleton Sarcoplasm Axon Growth Cone Midbody Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Axon Cytoplasm	Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Negative Regulation Of Protein Kinase Activity Blood Coagulation Anterograde Axonal Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Negative Regulation Of Protein Binding Melanosome Organization Regulation Of JUN Kinase Activity Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Dendrite Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Exocytosis	Regulation Of Transcription By RNA Polymerase II
Pathways		Golgi Associated Vesicle Biogenesis	Generic Transcription Pathway
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Corneal astigmatism ( 30306274) Multiple myeloma ( 27363682) Squamous cell carcinoma ( 31174203)	Adult body size ( 32376654)
Interacting Genes		50 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S5 BLOC1S6 BRF1 CCDC146 CCDC153 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 KRT75 MACF1 NBEA NDN NECAB2 NUF2 OIP5 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM9 VRK2 WASHC3 ZNF490	34 interacting genes: CCDC136 CCNDBP1 CEP70 DTNBP1 FSD2 GLRX3 GOLGA6L9 HAP1 HOXB13 KRT40 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP12-3 LMNA LZTR1 LZTS2 MDFI MEOX2 MTUS2 NDEL1 RBMX RNPS1 STX1A TBX21 TEX19 TRAF1 TRIM41 TSGA10 VWC2 ZBTB32 ZC4H2 ZRANB1
Entrez ID		84062	57474
HPRD ID		06190	15802
Ensembl ID		ENSG00000047579	ENSG00000188033
Uniprot IDs		A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8	Q9ULM2
PDB IDs
Enriched GO Terms of Interacting Partners?
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