ROPN1L and AKAP5

Data Source:
BioGRID (two hybrid)

		ROPN1L	AKAP5
Description		rhophilin associated tail protein 1 like	A-kinase anchoring protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cilium Motile Cilium	Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Dendrite Membrane Dendritic Spine Membrane Raft Excitatory Synapse Postsynaptic Recycling Endosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Calmodulin Binding Adenylate Cyclase Binding SH3 Domain Binding Protein Phosphatase 2B Binding Beta-2 Adrenergic Receptor Binding Protein Kinase A Regulatory Subunit Binding Glutamate Receptor Binding GABA Receptor Binding Protein Kinase A Binding Molecular Adaptor Activity Scaffold Protein Binding
	Biological Process	Regulation Of Protein Phosphorylation Epithelial Cilium Movement Involved In Extracellular Fluid Movement Flagellated Sperm Motility Sperm Capacitation	Signal Transduction Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Chemical Synaptic Transmission Regulation Of Protein Kinase A Signaling Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endosome To Plasma Membrane Protein Transport
Pathways			Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Trafficking of AMPA receptors ROBO receptors bind AKAP5 ROBO receptors bind AKAP5
Drugs
Diseases
GWAS		Body mass index ( 22446040) Breast cancer ( 21424380) Coronary artery disease in type 1 diabetes ( 29695241) Dermatomyositis or juvenile dermatomyositis ( 26362759) Mean arterial pressure ( 27618448) Triglyceride levels ( 31170924)
Interacting Genes		8 interacting genes: AKAP14 AKAP3 AKAP5 AKAP7 APP BEX2 RSPH3 SPA17	21 interacting genes: ADRB2 CALM1 DLG1 DLG4 FOS GABRB1 GABRB3 IQGAP1 JUN KCNJ2 MDM2 PPP3CA PRKAR1A PRKAR2A PRKAR2B PRKCA RET ROPN1 ROPN1L TP53 TRPV1
Entrez ID		83853	9495
HPRD ID		17986	05255
Ensembl ID		ENSG00000145491	ENSG00000179841
Uniprot IDs		Q96C74	P24588 Q6PG46
PDB IDs			2H9R 3LL8 5NIN
Enriched GO Terms of Interacting Partners?
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