CCM2 and RIN1

Data Source:
BioGRID (two hybrid)

		CCM2	RIN1
Description		CCM2 scaffold protein	Ras and Rab interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Protein-containing Complex	Cytoplasm Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding
	Biological Process	Vasculogenesis In Utero Embryonic Development Endothelial Cell Development Integrin-mediated Signaling Pathway Multicellular Organism Growth Cell-cell Junction Organization Inner Ear Development Venous Blood Vessel Morphogenesis Stress-activated MAPK Cascade Pericardium Development Blood Vessel Endothelial Cell Differentiation Endothelial Tube Morphogenesis	Endocytosis Signal Transduction Positive Regulation Of GTPase Activity
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Cerebral cavernous malformation
GWAS		Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		6 interacting genes: HOXC8 POT1 RIN1 SMURF1 SRPK2 TLNRD1	50 interacting genes: ABL1 ABL2 AFDN ANKS1A ANKS1B CALCOCO2 CAPNS2 CARD10 CCM2 CRACR2B EGFR EIF3F ERBB2 ERBB3 GOLGA2 GOLGA6L9 HMG20A HRAS HSF2BP KLHL12 KRT34 KRTAP13-1 KRTAP15-1 LZTS2 MDFI MTDH NRAS PICK1 PLEKHG4 RAB5A RAB5B RALGDS RRAS2 SEC23B SH3RF1 SNX17 SORBS3 SPRED1 TBC1D1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM7 TRIP10 TSC1 YWHAB YWHAE YWHAZ ZBED1
Entrez ID		83605	9610
HPRD ID		09719	05813
Ensembl ID		ENSG00000136280	ENSG00000174791
Uniprot IDs		B7Z8D5 Q9BSQ5	A0A0S2Z4U0 Q13671
PDB IDs		4FQN 4TVQ 4WJ7 4Y5O 4YKC 4YKD 4YL6
Enriched GO Terms of Interacting Partners?
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