SOX7 and SCAI

Data Source:
BioGRID (two hybrid)

		SOX7	SCAI
Description		SRY-box transcription factor 7	suppressor of cancer cell invasion
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Cytoplasm Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Endoderm Formation Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Canonical Wnt Signaling Pathway	Transcription, DNA-templated Negative Regulation Of Cell Migration Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of Transcription, DNA-templated
Pathways		Deactivation of the beta-catenin transactivating complex	RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Anxiety/tension (special factor of neuroticism) ( 30867560) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder ( 30804558) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Gut microbiota (beta diversity) ( 27723756) HDL cholesterol levels ( 32203549) Intracranial aneurysm ( 29531279) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Number of sexual partners ( 30643258) Processed meat consumption ( 32066663) Refractive error ( 32231278) Retinal vascular caliber ( 21060863) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Triglyceride levels ( 32154731) White blood cell count ( 32888494 27863252)	Pulse pressure ( 28135244 30578418) Refractive error ( 32231278) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		5 interacting genes: APP GLRX3 SCAI SMAD5 SMAD7	5 interacting genes: CDIPT ITPKB OGT PIN1 SOX7
Entrez ID		83595	286205
HPRD ID		18087	12941
Ensembl ID		ENSG00000171056	ENSG00000173611
Uniprot IDs		Q9BT81	Q8N9R8
PDB IDs
Enriched GO Terms of Interacting Partners?
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