RILP and SNF8

Data Source:
BioGRID (pull down)

		RILP	SNF8
Description		Rab interacting lysosomal protein	SNF8 subunit of ESCRT-II
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GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Late Endosome Cytosol Phagocytic Vesicle Membrane Late Endosome Membrane Protein-containing Complex Ciliary Basal Body	ESCRT II Complex Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding Protein Dimerization Activity Dynein Light Intermediate Chain Binding	Protein Binding Protein C-terminus Binding Transcription Factor Binding Channel Regulator Activity Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Endosome To Lysosome Transport Regulation Of Multivesicular Body Size Protein Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Protein Catabolic Process Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Cilium Assembly Intralumenal Vesicle Formation	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Regulation Of Multivesicular Body Size Involved In Endosome Transport Endosomal Transport Macroautophagy Endocytic Recycling Multivesicular Body Assembly Regulation Of Protein Catabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Regulation Of Protein Complex Stability Multivesicular Body Sorting Pathway Positive Regulation Of Exosomal Secretion Regulation Of Viral Budding Via Host ESCRT Complex
Pathways		MHC class II antigen presentation	Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS			Coronary heart disease ( 21378990) Type 2 diabetes ( 29358691)
Interacting Genes		12 interacting genes: KPNA2 LDB2 RAB34 RAB7A RCHY1 SNF8 VPS11 VPS16 VPS18 VPS36 VPS39 VPS41	24 interacting genes: ADORA1 AKAP9 CHMP6 CLP1 CT55 DVL2 ELL FANCL GLYCTK GOLGA2 KDM1A NIF3L1 PRMT6 RILP SMARCD1 SUOX SUV39H2 TRIM54 TSG101 TXLNA VAC14 VPS25 VPS36 YWHAE
Entrez ID		83547	11267
HPRD ID		09706	16847
Ensembl ID		ENSG00000167705	ENSG00000159210
Uniprot IDs		Q96NA2	Q96H20
PDB IDs		1YHN	2ZME 3CUQ
Enriched GO Terms of Interacting Partners?
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