NUF2 and AZGP1

Data Source:
BioGRID (two hybrid)

		NUF2	AZGP1
Description		NUF2 component of NDC80 kinetochore complex	alpha-2-glycoprotein 1, zinc-binding
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Membrane Ndc80 Complex	Extracellular Region Extracellular Space Nucleus External Side Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding Protein-containing Complex Binding	Ribonuclease Activity Protein Binding Protein Transmembrane Transporter Activity
	Biological Process	Mitotic Spindle Organization Chromosome Segregation Meiotic Chromosome Segregation Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Organization	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Immune Response Cell Adhesion Negative Regulation Of Cell Population Proliferation Transmembrane Transport Protein Transmembrane Transport RNA Phosphodiester Bond Hydrolysis
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Miscellaneous transport and binding events
Drugs			N-acetyl-alpha-neuraminic acid Copper
Diseases
GWAS		Asthma ( 29273806) Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168) Chronic obstructive pulmonary disease (moderate to severe) ( 24621683) Diffusing capacity of carbon monoxide ( 30694715) Height ( 28552196) Myopia ( 27182965)	Brain morphology (MOSTest) ( 32665545) Red blood cell count ( 27863252) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: ATF3 AURKA AURKB AZGP1 CENPE CENPH DTNBP1 EXOC1 NDC80 SDCBP2	5 interacting genes: ABCC1 ITGAV NUF2 SHBG UBQLN2
Entrez ID		83540	563
HPRD ID		10817	01910
Ensembl ID		ENSG00000143228	ENSG00000160862
Uniprot IDs		Q9BZD4	A0A140VK00 P25311
PDB IDs		2VE7 3IZ0	1T7V 1T7W 1T7X 1T7Y 1T7Z 1T80 1ZAG 3ES6 6R2U
Enriched GO Terms of Interacting Partners?
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