SERF1A and ELOVL7

Data Source:
BioGRID (two hybrid)

		SERF1A	ELOVL7
Description		small EDRK-rich factor 1A	ELOVL fatty acid elongase 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding Fatty Acid Elongase Activity 3-oxo-arachidoyl-CoA Synthase Activity 3-oxo-cerotoyl-CoA Synthase Activity 3-oxo-lignoceronyl-CoA Synthase Activity Very-long-chain 3-ketoacyl-CoA Synthase Activity
	Biological Process	Nervous System Development Protein Destabilization Amyloid Fibril Formation	Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Sphingolipid Biosynthetic Process Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Polyunsaturated Fatty Acid Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process
Pathways			Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean platelet volume ( 32888494 27863252) Multiple system atrophy ( 27629089) Parkinson's disease ( 32201043 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Subcortical volume (MOSTest) ( 32665545) Working memory ( 31598132)
Interacting Genes		15 interacting genes: ABHD16A APP AQP6 CERS4 CRB3 ELOVL4 ELOVL7 GPR152 LRRK2 PIK3R3 REEP4 RNASEK TIMMDC1 TMEM14B TMX2	12 interacting genes: ADGRE2 DTNBP1 EMP3 LRCH4 RTP2 SERF1A SERF1B SLC41A1 SYNJ2BP TMEM14C UBE2J2 VAMP1
Entrez ID		8293	79993
HPRD ID		04308	18700
Ensembl ID		ENSG00000172058	ENSG00000164181
Uniprot IDs		O75920	A1L3X0 D6RHD0
PDB IDs			6Y7F
Enriched GO Terms of Interacting Partners?
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