CLPP and TNFSF9

Data Source:
BioGRID (affinity chromatography technology)

		CLPP	TNFSF9
Description		caseinolytic mitochondrial matrix peptidase proteolytic subunit	TNF superfamily member 9
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Endopeptidase Clp Complex	Extracellular Space Plasma Membrane Integral Component Of Membrane
	Molecular Function	Endopeptidase Activity ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Identical Protein Binding ATPase Binding	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor Receptor Superfamily Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Membrane Protein Proteolysis Proteolysis Involved In Cellular Protein Catabolic Process	Immune Response Cell-cell Signaling Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Activated T Cell Proliferation Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Cytotoxic T Cell Differentiation
Pathways			TNFs bind their physiological receptors
Drugs		N-Formylmethionine
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: ABI2 C14orf119 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS TNPO3 TRIM54	3 interacting genes: TNFRSF9 TRAF1 TRAF2
Entrez ID		8192	8744
HPRD ID		03074	05861
Ensembl ID		ENSG00000125656	ENSG00000125657
Uniprot IDs		Q16740	A0A0U5J8I0 P41273
PDB IDs		1TG6 6BBA 6DL7 6H23	2X29 6A3V 6BWV 6CPR 6CU0 6D3N 6FIB 6MGE 6MGP
Enriched GO Terms of Interacting Partners?
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