TRIM56 and MIR25

Data Source:
BioGRID (unspecified method)

		TRIM56	MIR25
Description		tripartite motif containing 56	microRNA 25
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytoplasm Cytosol	Extracellular Space
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Regulation Of Type I Interferon Production Interferon-beta Production Response To Type I Interferon Innate Immune Response Positive Regulation Of Transcription, DNA-templated Defense Response To Virus Protein K63-linked Ubiquitination	Gene Silencing By MiRNA Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways		Regulation of innate immune responses to cytosolic DNA
Drugs
Diseases
GWAS		Alzheimer's disease ( 30636644) Nonunion in individuals with fractures ( 30680360)
Interacting Genes		4 interacting genes: MIR200C MIR25 MIR34B UBE2H	100 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PATL1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM17 RBM4 RBM45 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM56 TRIM71 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		81844	407014
HPRD ID		10284
Ensembl ID		ENSG00000169871	ENSG00000207547
Uniprot IDs		Q9BRZ2
PDB IDs		5JW7
Enriched GO Terms of Interacting Partners?
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