RNF170 and STARD3

Data Source:
BioGRID (two hybrid)

		RNF170	STARD3
Description		ring finger protein 170	StAR related lipid transfer domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleoplasm Cytoplasm Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Cholesterol Binding Protein Homodimerization Activity Cholesterol Transfer Activity
	Biological Process	Protein Ubiquitination	Lipid Metabolic Process C21-steroid Hormone Biosynthetic Process Mitochondrial Transport Steroid Metabolic Process Cholesterol Metabolic Process Cholesterol Transport Vesicle Tethering To Endoplasmic Reticulum Intermembrane Lipid Transfer
Pathways			Pregnenolone biosynthesis
Drugs
Diseases
GWAS			Alcohol consumption ( 31358974) Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Hemoglobin levels ( 32327693) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Smoking behaviour (cigarettes smoked per day) ( 30679032) Triglyceride levels ( 30108155) Ulcerative colitis ( 20228799)
Interacting Genes		16 interacting genes: DNAJC30 FXYD6-FXYD2 HACD1 PLPP6 PSMA6 SGTA SGTB SLC35B2 SNAP47 STARD3 TMEM109 TMEM97 UBE2D2 UBE2L3 UBE2U UPK2	6 interacting genes: AQP6 CREB3 DAPK1 GOPC LMNA RNF170
Entrez ID		81790	10948
HPRD ID		13165	06132
Ensembl ID		ENSG00000120925	ENSG00000131748
Uniprot IDs		Q96K19	Q14849
PDB IDs			1EM2 2I92 5I9J
Enriched GO Terms of Interacting Partners?
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