FIP1L1 and CPSF4

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		FIP1L1	CPSF4
Description		factor interacting with PAPOLA and CPSF1	cleavage and polyadenylation specific factor 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Export From Nucleus MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs Signaling by cytosolic PDGFRA and PDGFRB fusion proteins	Transport of Mature mRNA Derived from an Intronless Transcript Inhibition of Host mRNA Processing and RNA Silencing tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) DNA methylation (variation) ( 23725790) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Red blood cell count ( 28453575) Serum VEGFR2 concentration ( 25411163) Subcortical volume (MOSTest) ( 32665545)	Diffuse cutaneous systemic sclerosis ( 29293537) Facial emotion recognition (sad faces) ( 28608620) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Serum metabolite levels ( 23093944) Tacrolimus trough concentration in kidney transplant patients ( 29160300)
Interacting Genes		29 interacting genes: APP CPSF4 CSNK2A1 GOLGA2 HMGB1 LIG4 MIR128-2 MIR15B MIR16-2 MIR19A MIR19B1 MIR205 MIR221 MIR34A MIR34B MIR9-3 MIR92A1 MIR92A2 MIRLET7B MIRLET7G MIRLET7I NAA10 PAPOLA PRMT2 PRMT6 SGTA SRPK2 WWOX ZMYND19	10 interacting genes: CREBBP FIP1L1 MARK3 MEOX2 MID2 MIR19A MIR19B1 MIR92A2 MYOG SLC12A9
Entrez ID		81608	10898
HPRD ID		09646	04338
Ensembl ID		ENSG00000145216	ENSG00000160917
Uniprot IDs		Q6UN15	B7Z7B0 O95639
PDB IDs			2D9N 2RHK 6DNH 6FBS 6FUW 6URG 6URO
Enriched GO Terms of Interacting Partners?
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