RND2 and FNBP1

Data Source:
HPRD (in vitro, two hybrid)

		RND2	FNBP1
Description		Rho family GTPase 2	formin binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Early Endosome Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Protein N-terminus Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Cell Shape Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Collateral Sprouting	Endocytosis Signal Transduction Membrane Organization
Pathways			Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688) Physiological dysregulation (Mahalanobis distance) ( 32235003)
Interacting Genes		6 interacting genes: ARHGAP5 FNBP1 MEOX2 RACGAP1 UBXN11 VPS4A	13 interacting genes: AGTR1 AKAP9 ARHGAP17 CBL CDC42 DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL
Entrez ID		8153	23048
HPRD ID		03332	10446
Ensembl ID		ENSG00000108830	ENSG00000187239
Uniprot IDs		P52198	B7ZL13 B7ZL14 Q96RU3
PDB IDs			2EFL
Enriched GO Terms of Interacting Partners?
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