CFHR5 and KCNK7

Data Source:
BioGRID (two hybrid)

		CFHR5	KCNK7
Description		complement factor H related 5	potassium two pore domain channel subfamily K member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Protein-containing Complex	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Voltage-gated Ion Channel Activity Potassium Channel Activity Potassium Ion Leak Channel Activity
	Biological Process	Complement Activation, Alternative Pathway Regulation Of Complement Activation Negative Regulation Of Protein Binding Cytolysis By Host Of Symbiont Cells	Potassium Ion Transport Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Regulation of Complement cascade	Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) Phase 4 - resting membrane potential
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) Age-related macular degeneration (MTAG) ( 32277175) Asthma ( 29273806) Blood protein levels ( 29875488 28240269) Lupus nephritis in systemic lupus erythematosus ( 24925725) Matrix metalloproteinase-8 levels ( 29212897) Nephropathy ( 21399633)	Acne (severe) ( 24927181) Rosacea symptom severity ( 29771307)
Interacting Genes		20 interacting genes: ARL13B C3 CISD2 CREB3 CREB3L1 EBAG9 ERGIC3 FFAR2 GPX8 KCNK7 LMNA MFSD14B PANX1 SLC10A1 SLC18A2 SLC4A1 STOM TMEM14B TMEM237 TMPRSS2	1 interacting genes: CFHR5
Entrez ID		81494	10089
HPRD ID		06508	06804
Ensembl ID		ENSG00000134389	ENSG00000173338
Uniprot IDs		Q9BXR6	A0A024R5B0 A0A024R5F5 Q3SYI1 Q9Y2U2
PDB IDs
Enriched GO Terms of Interacting Partners?
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