PABPN1 and PRMT3

Data Source:
HPRD (in vitro)

		PABPN1	PRMT3
Description		poly(A) binding protein nuclear 1	protein arginine methyltransferase 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Nuclear Inclusion Body Ribonucleoprotein Complex	Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding RNA Polymerase Binding	Protein Binding Methyltransferase Activity Protein-arginine N-methyltransferase Activity Ribosome Binding Metal Ion Binding
	Biological Process	MAPK Cascade MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction Poly(A)+ MRNA Export From Nucleus MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing Cellular Response To Lipopolysaccharide Positive Regulation Of Polynucleotide Adenylyltransferase Activity	Protein Methylation Negative Regulation Of Protein Ubiquitination Peptidyl-arginine N-methylation
Pathways		Inhibition of Host mRNA Processing and RNA Silencing mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	RMTs methylate histone arginines Protein methylation
Drugs			S-adenosyl-L-homocysteine
Diseases		Oculopharyngeal muscular dystrophy (OPMD)
GWAS		Body mass index ( 26865924) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		13 interacting genes: CARM1 DNAJB4 HNRNPA1 HSP90AA1 IL7R LATS1 LINC00839 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ	11 interacting genes: BEND7 FBL HNRNPA1 MEOX2 PABPN1 PIH1D2 PPARD RASSF2 RPS2 STAT1 TSC22D2
Entrez ID		8106	10196
HPRD ID		03787	11934
Ensembl ID		ENSG00000100836	ENSG00000185238
Uniprot IDs		Q86U42	O60678 Q8WUV3
PDB IDs		3B4D 3B4M 3UCG	2FYT 3SMQ 4HSG 4QQN 4RYL
Enriched GO Terms of Interacting Partners?
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