CALML3 and MYO10

Data Source:
HPRD (two hybrid, in vivo)

		CALML3	MYO10
Description		calmodulin like 3	myosin X
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GO Annotations	Cellular Component	Extracellular Exosome	Ruffle Nucleolus Cytosol Plasma Membrane Cell Cortex Myosin Complex Lamellipodium Filopodium Membrane Filopodium Tip
	Molecular Function	Calcium Ion Binding Protein Binding Enzyme Regulator Activity	Protein Binding Calmodulin Binding ATP Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Spectrin Binding Actin-dependent ATPase Activity Actin Filament Binding Plus-end Directed Microfilament Motor Activity
	Biological Process	Regulation Of Catalytic Activity	Regulation Of Cell Shape Cytoskeleton-dependent Intracellular Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Filopodium Assembly
Pathways			Regulation of actin dynamics for phagocytic cup formation Netrin-1 signaling FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS			Body mass index (change over time) in lung cancer or chronic obstructive pulmonary disease ( 28044437) Circulating odd-numbered chain saturated fatty acid levels (C17:0) ( 29738550) Major depressive disorder ( 23377640) Metabolite levels ( 23823483) Normal facial asymmetry (deformation magnitude) ( 30631343) Obesity-related traits ( 23251661) Response to antidepressants (symptom remission) ( 29160301) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		9 interacting genes: BHLHE40 C11orf65 IQCB1 IQCN ISOC2 MAPK4 MFHAS1 MYO10 TERF2IP	6 interacting genes: ACTA1 CALM1 CALML3 DYNLL1 ITGB5 PLA2G10
Entrez ID		810	4651
HPRD ID		00244	03283
Ensembl ID		ENSG00000178363	ENSG00000145555
Uniprot IDs		P27482	Q9HD67
PDB IDs		1GGZ	2LW9 3AU4 3AU5 3PZD 5I0H 5I0I 5KG8
Enriched GO Terms of Interacting Partners?
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