B9D2 and PLEKHG2

Data Source:
BioGRID (affinity chromatography technology)

		B9D2	PLEKHG2
Description		B9 domain containing 2	pleckstrin homology and RhoGEF domain containing G2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Membrane MKS Complex Ciliary Basal Body	Cytosol
	Molecular Function	Protein Binding Gamma-tubulin Binding	Protein Binding
	Biological Process	Cilium Assembly Ciliary Basal Body-plasma Membrane Docking	G Protein-coupled Receptor Signaling Pathway Regulation Of Actin Filament Polymerization Positive Regulation Of Apoptotic Process Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Anchoring of the basal body to the plasma membrane RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Coronary artery disease ( 32469254 29212778) Preterm birth (maternal effect) ( 28877031) Pulse pressure ( 27841878)
Interacting Genes		8 interacting genes: ALKBH7 P4HA3 PLEKHA7 PPP1R32 QARS1 SPAG8 TLX3 VPS25	8 interacting genes: ACTN3 APP CDC42 GNG2 PIN1 RAC1 RHOA XRN1
Entrez ID		80776	64857
HPRD ID		14613	15148
Ensembl ID		ENSG00000123810	ENSG00000090924
Uniprot IDs		Q9BPU9	Q9H7P9
PDB IDs
Enriched GO Terms of Interacting Partners?
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