DCAF11 and TNNI2

Data Source:
BioGRID (two hybrid)

		DCAF11	TNNI2
Description		DDB1 and CUL4 associated factor 11	troponin I2, fast skeletal type
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Cytosol Troponin Complex
	Molecular Function	Protein Binding	Actin Binding Protein Binding Troponin T Binding
	Biological Process	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Skeletal Muscle Contraction Muscle Contraction Regulation Of Muscle Contraction Muscle Filament Sliding Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Contraction
Pathways		Neddylation	Striated Muscle Contraction
Drugs
Diseases			Distal arthrogryposis (DA)
GWAS			Celiac disease ( 23936387) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Inflammatory bowel disease ( 23128233) Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		13 interacting genes: AGR2 CDKN1A DDB1 GPSM1 NFE2L2 PTEN RCN1 SLBP TNNI1 TNNI2 TNS2 TRIM55 TRIM63	21 interacting genes: ACTB C1orf109 CALM1 CTNNA3 DCAF11 EFCAB2 ESRRA ESRRG HNF4G MNS1 NME7 PKD2L1 PSMC5 RORB TNNC1 TNNC2 TNNT1 TNNT3 TRIM55 TRIM63 UPF2
Entrez ID		80344	7136
HPRD ID		18297	01843
Ensembl ID		ENSG00000100897	ENSG00000130598
Uniprot IDs		B3KSW2 Q59GN6 Q8TEB1	P48788
PDB IDs			2MKP
Enriched GO Terms of Interacting Partners?
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