SLC8B1 and IFT81

Data Source:
BioGRID (proximity labelling technology)

		SLC8B1	IFT81
Description		solute carrier family 8 member B1	intraflagellar transport 81
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Plasma Membrane Membrane Mitochondrial Crista Integral Component Of Mitochondrial Membrane	Centrosome Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Ciliary Tip
	Molecular Function	Calcium:sodium Antiporter Activity Cation Transmembrane Transporter Activity Calcium:cation Antiporter Activity Protein Homodimerization Activity Calcium:sodium Antiporter Activity Involved In Regulation Of Cardiac Muscle Cell Membrane Potential	Protein Binding Tubulin Binding
	Biological Process	Ion Transport Cation Transport Mitochondrial Calcium Ion Transmembrane Transport Cellular Calcium Ion Homeostasis Sodium Ion Transmembrane Transport Glucose Homeostasis Regulation Of Insulin Secretion Response To Stimulus Regulation Of Cytosolic Calcium Ion Concentration Mitochondrial Calcium Ion Homeostasis Regulation Of Cardiac Muscle Cell Membrane Potential Calcium Export From The Mitochondrion Regulation Of Lymphocyte Chemotaxis Regulation Of Store-operated Calcium Entry	Spermatogenesis Regulation Of Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Cilium Assembly
Pathways		Sodium/Calcium exchangers Mitochondrial calcium ion transport	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Total intracranial volume ( 31530798)
Interacting Genes			2 interacting genes: APP IFT74
Entrez ID		80024	28981
HPRD ID		15354	09266
Ensembl ID		ENSG00000089060	ENSG00000122970
Uniprot IDs		Q6J4K2	A0A024RBJ1 Q8WYA0
PDB IDs
Enriched GO Terms of Interacting Partners?
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