IFT81 and IFT74

Data Source:
BioGRID (two hybrid)

		IFT81	IFT74
Description		intraflagellar transport 81	intraflagellar transport 74
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Ciliary Tip	Nucleus Centrosome Cilium Intraciliary Transport Particle B Cytoplasmic Vesicle Motile Cilium Ciliary Tip
	Molecular Function	Protein Binding Tubulin Binding	Chromatin Binding Protein Binding Beta-tubulin Binding
	Biological Process	Spermatogenesis Regulation Of Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Cilium Assembly	Keratinocyte Development Notch Signaling Pathway Determination Of Left/right Symmetry Heart Development Positive Regulation Of Cell Adhesion Mediated By Integrin Intraciliary Transport Involved In Cilium Assembly Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Epithelial Cell Proliferation Cilium Assembly Non-motile Cilium Assembly
Pathways		Intraflagellar transport Intraflagellar transport	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Total intracranial volume ( 31530798)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189)
Interacting Genes		2 interacting genes: APP IFT74	5 interacting genes: CCDC196 DISC1 HGS IFT81 SMARCE1
Entrez ID		28981	80173
HPRD ID		09266	09727
Ensembl ID		ENSG00000122970	ENSG00000096872
Uniprot IDs		A0A024RBJ1 Q8WYA0	Q96LB3
PDB IDs
Enriched GO Terms of Interacting Partners?
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