NAA25 and IFT81

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		NAA25	IFT81
Description		N-alpha-acetyltransferase 25, NatB auxiliary subunit	intraflagellar transport 81
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol NatB Complex	Centrosome Cilium Intraciliary Transport Particle B Motile Cilium Ciliary Basal Body Ciliary Tip
	Molecular Function	Peptide Alpha-N-acetyltransferase Activity Protein Binding	Protein Binding Tubulin Binding
	Biological Process	N-terminal Peptidyl-methionine Acetylation	Spermatogenesis Regulation Of Smoothened Signaling Pathway Intraciliary Transport Involved In Cilium Assembly Intraciliary Transport Cilium Assembly
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases		Type I diabetes mellitus
GWAS		Alcohol consumption (max-drinks) ( 29460428) Alcohol dependence symptom count ( 29460428) Body mass index ( 26426971) Chronotype ( 30696823) Coffee consumption ( 29367735) Coronary artery disease ( 30104761) Crohn's disease ( 28067908) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Estimated glomerular filtration rate ( 31152163) Gout (combined type) ( 32238385) Hypothyroidism ( 22493691) Inflammatory bowel disease ( 28067908) Mean arterial pressure ( 27618448) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Myocardial infarction ( 30226566) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Response to alcohol consumption (flushing response) ( 29460428) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Urate levels ( 31578528)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Headache ( 29397368) Intelligence (MTAG) ( 29326435) Total intracranial volume ( 31530798)
Interacting Genes		1 interacting genes: APP	2 interacting genes: APP IFT74
Entrez ID		80018	28981
HPRD ID		08578	09266
Ensembl ID		ENSG00000111300	ENSG00000122970
Uniprot IDs		Q14CX7	A0A024RBJ1 Q8WYA0
PDB IDs		6VP9
Enriched GO Terms of Interacting Partners?
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