WWC2 and REPS1

		WWC2	REPS1
Description		WW and C2 domain containing 2	RALBP1 associated Eps domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	Kinase Binding Molecular Adaptor Activity	Calcium Ion Binding Protein Binding SH3 Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hippo Signaling Negative Regulation Of Organ Growth	Endocytosis Receptor-mediated Endocytosis Endosomal Transport Membrane Organization
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Heel bone mineral density ( 30598549) Height ( 28552196 20881960) Initial alcohol sensitivity ( 30276832)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834) Type 2 diabetes ( 32499647)
Interacting Genes		4 interacting genes: REPS1 WWC1 WWC3 YWHAQ	17 interacting genes: ANKRD1 ATF4 CRK FLNC GRB2 HSF1 ITSN2 MZT1 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2 TRAPPC2L WWC2
Entrez ID		80014	85021
HPRD ID		12529	09687
Ensembl ID		ENSG00000151718	ENSG00000135597
Uniprot IDs		Q6AWC2	B2R7D3 Q96D71
PDB IDs
Enriched GO Terms of Interacting Partners?
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