SCD5 and TMEM176A

Data Source:
BioGRID (two hybrid)

		SCD5	TMEM176A
Description		stearoyl-CoA desaturase 5	transmembrane protein 176A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Stearoyl-CoA 9-desaturase Activity Iron Ion Binding Oxidoreductase Activity	Protein Binding
	Biological Process	Unsaturated Fatty Acid Biosynthetic Process Fatty-acyl-CoA Biosynthetic Process Monounsaturated Fatty Acid Biosynthetic Process	Negative Regulation Of Dendritic Cell Differentiation
Pathways		Fatty acyl-CoA biosynthesis EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS		Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Erosive tooth wear (severe vs non-severe) ( 29898447) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Lymphocyte counts ( 32888494 27863252) Monocyte count ( 29403010 32888494) Monocyte percentage of white cells ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Type 2 diabetes ( 30054458 30297969) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) White blood cell count ( 29403010 32888494) White blood cell count (basophil) ( 27863252)	Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Height ( 20881960 23563607) Metabolite levels ( 23823483) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		1 interacting genes: TMEM176A	16 interacting genes: CD79A CERS4 GOLM1 HIVEP1 KCNK5 MFSD14B MTIF3 RETREG3 RIDA SCD5 SGPL1 TGM2 TIMMDC1 TMEM176B TMX2 VKORC1
Entrez ID		79966	55365
HPRD ID		09756	13635
Ensembl ID		ENSG00000145284	ENSG00000002933
Uniprot IDs		Q86SK9 Q86UC8	A0A090N8H6 Q96HP8
PDB IDs
Enriched GO Terms of Interacting Partners?
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