PRR5L and ZMYND12

Data Source:
BioGRID (two hybrid)

		PRR5L	ZMYND12
Description		proline rich 5 like	zinc finger MYND-type containing 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TORC2 Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of Fibroblast Migration Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cellular Response To Oxidative Stress TORC2 Signaling Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Intracellular Protein Transport
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 31361310 30929738 32296059 31619474) Asthma (childhood onset) ( 30929738) Atopic dermatitis ( 26482879 23727859) Idiopathic inflammatory myopathy ( 26362759) Inflammatory skin disease ( 25574825) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Mean corpuscular volume ( 32888494) Multiple sclerosis ( 31604244 24076602) Photic sneeze reflex ( 27182965) Red blood cell count ( 32888494)
Interacting Genes		15 interacting genes: CCDC91 EFHC1 FHL2 FHL3 HSF2BP KANK2 MAD2L2 MISP MLH1 MORN3 MTOR PHAF1 SCNM1 USP2 ZMYND12	80 interacting genes: ABI2 ARHGAP8 ARMC8 ARNTL C1orf109 CCDC116 CCDC24 CHCHD2 CWF19L2 DMRT3 EVX2 FAM214B FAM222B FAM50B FAM90A1 GPKOW GSTZ1 HAPLN2 HDAC4 HOXB5 HOXC9 HR HSF4 ILF2 INCA1 KANK2 LENG1 LMO2 LMO4 MAD2L2 MNS1 MOAP1 MSGN1 MSRB3 NAB2 NUDT22 ONECUT3 PATL1 PICK1 POM121 POU6F2 PPP1R18 PPP1R32 PRKAA2 PRR35 PRR5-ARHGAP8 PRR5L PSMB8 QARS1 RIPPLY1 RUSC1 SAMD11 SAXO1 SCNM1 SDCBP SEC14L4 SH2D4A SHC3 SMARCD1 SMG9 SOHLH1 SPG21 STRA8 TEKT4 TEKT5 TEPSIN TFAP2D THOC1 THRSP TLE5 TSEN54 TSSK3 TTC29 TXN2 TYMP UNC5CL VEZF1 VPS37C ZNF148 ZNF414
Entrez ID		79899	84217
HPRD ID		07854	15740
Ensembl ID		ENSG00000135362	ENSG00000066185
Uniprot IDs		B3KNU3 Q6MZQ0	B4DX70 Q9H0C1
PDB IDs
Enriched GO Terms of Interacting Partners?
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