TCTN2 and CCDC92

Data Source:
BioGRID (two hybrid)

		TCTN2	CCDC92
Description		tectonic family member 2	coiled-coil domain containing 92
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Integral Component Of Membrane MKS Complex Ciliary Membrane	Nucleoplasm Cytoplasm Centrosome Centriole Intracellular Membrane-bounded Organelle
	Molecular Function		Protein Binding Identical Protein Binding
	Biological Process	Smoothened Signaling Pathway Cilium Assembly Ciliary Basal Body-plasma Membrane Docking Protein Localization To Ciliary Transition Zone
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Atrial fibrillation ( 29892015) Coronary artery disease ( 29212778 28714974) Hand grip strength ( 29691431) HDL cholesterol ( 20686565) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Lymphocyte counts ( 32888494) Metabolite levels ( 23823483) Monocyte count ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494) Triglyceride levels ( 32203549) Triglycerides ( 20686565) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference variance ( 31453325) Waist-to-hip ratio adjusted for BMI ( 26426971 30389748) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500) White blood cell count ( 32888494 27863252)
Interacting Genes			12 interacting genes: CEP76 CHGB COG6 DISC1 FHL2 GOLGA2 PLEKHA5 PSMD8 TP53BP2 TRIM27 TRIML2 UBC
Entrez ID		79867	80212
HPRD ID		07805	16919
Ensembl ID		ENSG00000168778	ENSG00000119242
Uniprot IDs		Q96GX1	Q53HC0
PDB IDs
Enriched GO Terms of Interacting Partners?
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