ZC2HC1C and CLIC3

Data Source:
BioGRID (two hybrid)

		ZC2HC1C	CLIC3
Description		zinc finger C2HC-type containing 1C	chloride intracellular channel 3
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Nuclear Body Chloride Channel Complex Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process		Glutathione Metabolic Process Chloride Transport Signal Transduction Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Refractive error ( 32231278)
Interacting Genes		80 interacting genes: ACTN2 ANKS1A ARMC7 BANP BICD2 BYSL C19orf54 CABP5 CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CCDC85B CCDC88B CIB3 CLIC3 CRACR2A DDX6 EMILIN1 ENKD1 FAM90A1 FBXO7 FGFR1OP2 FSD2 GFAP GOLGA1 GOLGA2 GOLGA6A GPRASP2 HOOK2 HSF2BP KASH5 KAT5 KATNBL1 KIF9 KRT15 KRT20 KRT40 LMNA LMNB2 LZTS2 MAPK9 MAPRE3 MID2 MTUS2 NCKIPSD NDEL1 NDOR1 NEK6 NOXA1 NTAQ1 OSGIN1 PFDN5 PIBF1 PNMA1 POLR1C PRKAB2 PSTPIP1 RABGEF1 RAD51D RINT1 SFN SIKE1 SMARCD1 SORBS3 SPAG5 TFIP11 TNPO2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM55 TRIM63 UBASH3A VPS52 ZNF655 ZNF76	35 interacting genes: AGR2 ALX1 ANKRD23 ANKRD55 APP C7orf31 C9orf24 DDIT4L DNM1 EFHC2 FAM166B GLYR1 INCA1 KATNBL1 KRT85 KRTAP13-3 LELP1 MAPK15 MBD3L1 MECOM MIA3 MSX2 POT1 PROSER2 SCML4 STMN3 TBC1D3 TBC1D3C TBC1D3K TEPSIN TLE5 VPS4A ZBTB42 ZC2HC1C ZNF620
Entrez ID		79696	9022
HPRD ID		16607	05941
Ensembl ID		ENSG00000119703	ENSG00000169583
Uniprot IDs		A0A024R6E6 H0YE08 J3KMY6 Q53FD0	O95833 Q6FGP1
PDB IDs			3FY7 3KJY
Enriched GO Terms of Interacting Partners?
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