BEND5 and CTNNBIP1

Data Source:
HPRD (two hybrid)

		BEND5	CTNNBIP1
Description		BEN domain containing 5	catenin beta interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus	Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex
	Molecular Function	DNA Binding Protein Binding	Protein Binding Beta-catenin Binding Armadillo Repeat Domain Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated	Branching Involved In Ureteric Bud Morphogenesis Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Protein Binding Negative Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Mesenchymal Cell Proliferation
Pathways			Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS			Platelet distribution width ( 32888494) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		27 interacting genes: APP BUD31 CTNNBIP1 DDR1 EIF3D ERBB3 FAM161A GFI1B GORASP2 GRAP2 LCE1B LMO3 NTAQ1 PIMREG PRKAB2 PTGR2 RTP5 SMARCD1 TSPOAP1 UBE2I USP2 USP20 USP7 VPS25 ZGPAT ZNF417 ZNF688	19 interacting genes: BEND5 CTNNA2 CTNNB1 EMD GINS4 INCA1 JUP KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP5-9 MSS51 NBPF19 NOTCH2NLA P4HA3 REL SPATA24 TCF7L2 USHBP1
Entrez ID		79656	56998
HPRD ID		07756	09677
Ensembl ID		ENSG00000162373	ENSG00000178585
Uniprot IDs		A0A0S2Z5N0 Q7L4P6	A0A024R4D7 Q9NSA3
PDB IDs			1LUJ 1M1E 1T08
Enriched GO Terms of Interacting Partners?
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