BIRC7 and PRR35

Data Source:
BioGRID (two hybrid)

		BIRC7	PRR35
Description		baculoviral IAP repeat containing 7	proline rich 35
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Enzyme Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Lens Development In Camera-type Eye Apoptotic Process Activation Of JUN Kinase Activity Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Regulation Of Cell Cycle Regulation Of Natural Killer Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes		37 interacting genes: AURKC BOLA1 BOLA2 BOLA2B CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B GTF2A1 HTRA2 KANK2 LCOR LMO4 NTAQ1 PHF1 POLR1C PRR35 PSMB1 PTCD3 QARS1 SOX5 TEPSIN TLE5 TNPO2 TSGA10IP TTPA UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K USP2 VPS37C XAF1	80 interacting genes: ABHD11 ACY1 APPL2 ARMC5 ASB15 BEGAIN BIRC7 BPIFA1 C11orf1 C19orf54 CARD10 CCDC136 CNOT2 CRX CYSRT1 EXOC8 FAM168B FHL3 FRYL GIGYF1 GRAP2 HOMER3 HOOK2 HPCA HSPB2 HSPB2-C11orf52 INSC INTS11 JUP KLHL26 KRT31 KRT34 KRT35 KRTAP10-7 KRTAP12-1 KRTAP26-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LASP1 LONRF1 LZTS2 MAGED1 MCCD1 MKRN3 MSS51 MTUS2 N4BP3 NBPF19 NOTCH2NLA OIP5 OXER1 PFDN5 PLAGL2 PPIL1 PPP1R13B PRR20A PRR20B PRR20C PRR20D PRR20E PSTPIP1 RBPMS RNF144B RUSC1 SMUG1 SPAG8 TBX19 TLE5 TRIM27 TRIM54 TRIM73 TTC19 TTLL12 UBASH3B UBXN11 USP54 ZMYND12 ZNF655
Entrez ID		79444	146325
HPRD ID		05761	10046
Ensembl ID		ENSG00000101197	ENSG00000161992
Uniprot IDs		Q96CA5	P0CG20
PDB IDs		1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?
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