FYCO1 and MON1A

Data Source:
HPRD (in vivo)

		FYCO1	MON1A
Description		FYVE and coiled-coil domain autophagy adaptor 1	MON1 homolog A, secretory trafficking associated
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Late Endosome Autophagosome Golgi Apparatus Membrane Intracellular Membrane-bounded Organelle	Cytosol Mon1-Ccz1 Complex
	Molecular Function	Protein Binding Metal Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Autophagosome Maturation	Protein Targeting To Vacuole Protein Secretion Vesicle-mediated Transport Regulation Of Catalytic Activity
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)	Age at first birth ( 27798627) Body mass index ( 28892062 25673413 29273807) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		4 interacting genes: APP KDM1A PRMT6 RAF1	6 interacting genes: GFI1B MAPK6 RABGEF1 RGS2 TAB1 VPS33A
Entrez ID		79443	84315
HPRD ID		06215	17586
Ensembl ID		ENSG00000163820	ENSG00000164077
Uniprot IDs		Q9BQS8	Q86VX9
PDB IDs		5CX3 5D94 7BQI
Enriched GO Terms of Interacting Partners?
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