LRRC2 and TP53RK

Data Source:
BioGRID (two hybrid)

		LRRC2	TP53RK
Description		leucine rich repeat containing 2	TP53 regulating kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Intracellular Membrane-bounded Organelle	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Serine/threonine Phosphatase Activity	P53 Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Hydrolase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Protein Dephosphorylation Signal Transduction	Protein Phosphorylation TRNA Processing TRNA Threonylcarbamoyladenosine Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator
Pathways			tRNA modification in the nucleus and cytosol Regulation of TP53 Activity through Phosphorylation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Coronary atherosclerosis (time to event) ( 32589924) Metabolite levels ( 23823483) Refractive error ( 32231278)	Dimensional psychopathology (Arousal) ( 29496196) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		1 interacting genes: TP53RK	12 interacting genes: CALCOCO2 CHN2 CLK1 DCTN1 GORASP2 LRRC2 MDM2 MTUS2 OSGEP SYNE1 TP53 TPRKB
Entrez ID		79442	112858
HPRD ID		06213	12276
Ensembl ID		ENSG00000163827	ENSG00000172315
Uniprot IDs		Q9BYS8	Q96S44
PDB IDs
Enriched GO Terms of Interacting Partners?
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